14-Dec-2020 | Market Research Store
Researchers have recently found that blocking a specific protein for a month can help regain the mass and strength in the animals just like in the mice models. The researchers from the Stanford University School of Medicine have found that increasing the expression of the protein can weaken or cause muscle atrophy. The need for a better treatment to strengthen muscle fibers is important as humans tend to lose about 10% of their muscle strength per decade after about age 50. It is for the first time that the protein has been linked with aging. The protein named “15-PGDH” has been found to have decreased in older mice and also expressed in large amounts in the old tissues. There are hopes that a new future treatment for the weakening of muscles in the elderly is possible.
Generally, the muscle loss which is commonly known as sarcopenia costs billions of dollars for the healthcare expenditure in the U.S on an annual basis. It is thus important that a new solution that is cost-effective and efficient is developed as muscle weakness could lead to immobility and other health issues later in life. The changes in the muscle structure and function occur due to the alterations in the cellular powerhouse which is mitochondria. The muscle injury or diseases including Duchenne muscular dystrophy is the primary reason behind encouraging researchers to look for new solutions. Earlier, it was found that prostaglandin E2 helped activate muscle cells by repairing the damaged muscle fibers.
Enticingly, the researchers gathered more information on the PGE2’s potent dual function. In addition to this, they also found prostaglandin E2 levels to be regulated as well as broken down by 15-PGDH. Thus, studying the 15-PGDH levels in the human muscle tissues from people in their 70s or 80s could help better understand the importance of this protein in muscle regrowth. Even though beneficial information regarding the protein was gained but translating it into a therapy is still found to be difficult. However, the inhibition of 15-PGDH was shown to help improve bodywide muscle in the aged group.The idea of developing a new treatment is projected to help tone and strengthen muscles.
Market Research Store has published a report on global muscle atrophy market. The report covers the changing competitive market dynamics including economic fluctuations, market drivers, restraints, opportunities, regional development, latest technological innovations, and future scope.
https://www.marketresearchstore.com/report/global-muscle-atrophy-market-research-report-2018-273383