03-Sep-2021 | Market Research Store
Researchers from the University of California have recently uncovereda new finding that underlines the compounds present in both green and black tea which relaxes blood levels by activating ion channel proteins present in the blood vessel wall. The following discovery is aimed at helping to exert a longer list of antihypertensive properties of tea that could lead to designing a new form of new blood pressure lowering medications. The team hypothesizes that the KCNQ5 potassium channel is expected to activate at an accelerated rate under vasodilation which are often activated by consumption of tea.
The findings of these studies revealed that two catechin-type flavonoid compounds (epicatechin gallate and epigallocatechin-3-gallate) found in tea can activate a specific type of ion channel in a protein named KCNQ5 which activates after diffusion of cells under reduced cellular excitability.The research team notes that KCNQ5 is foundin the smooth muscle group that underline the blood vessels by a regulated consumption of tea catechins. The team integrated computer modelling models and mutagenesis studies in order to propagate the bindings of the catechins that bind to the foot of the voltage sensor which is responsible for increased cellular excitation.
The team notes that nearly one third of the world’s population suffers from hypertension as this condition is often considered to be a modifiable factor that pertains to the risk of a wider array of cardiovascular diseases and increases premature mortality. Previous studies interpreted that regulated amount of green and black tea can help reduce blood pressure by small yet consistent amount while catechins were found to contribute to the latter; however, the reasons were yet to be highlighted. This study underlines the component of NCNQ5 as the primary link between the suggested medicinal chemistry and further improve viability and potency of the following reaction.
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https://www.marketresearchstore.com/market-insights/green-tea-market-786119