27-Jun-2020 | Market Research Store
New drugs are likely to get approval fast if it can target a gene that is known to be linked with the disease. This was a recent finding and many pharmaceutical companies can gain from this while focusing on the drug development. This finding from Emily King and colleagues has been published in the PLOS Genetics.
A low percent of potential new drugs that are being developed pass through the early stage of the clinical trials. The percentage is around 5 to 10% which only cause losses to the pharmaceutical companies owing to the loss of capital in the development of the drugs.
King and colleagues worked on a study that was published in 2015 that claimed that drug approvals can be speedier if only they work on a protein linked to the targeted disease. With the use of advanced statistical analyses, the researchers tried to find which kind of genetic evidence can be helpful for providing drug discovery guidance. Their findings were influenced from the past studies which showcased that the drugs that were developed to target proteins with amino acid sequence changes made links with the disease and got better chances of approval. The research also showed that drugs that had genetic links to disparate diseases couldn’t get approvals as they were off-targets and may lead to negative side-effects.
Emily King made the statement, “The findings from this study demonstrate that human genetics evidence is predictive of historical drug development success. Moving forward, we believe that a more detailed understanding of the links between genetic variants and diseases will only continue to help scientists design more successful drug development programs.”
Howard Jacob, head of genomic research and vice president, of AbbVie further added that human genetics is a boon and it can help the drug development programs to focus and invest correctly on the drugs that impact the disease.
Market Research Store has published the latest report on the global genetic vaccine market which showcases the importance of the market and how its demand will increase in the coming years.
https://www.marketresearchstore.com/report/global-genetic-vaccine-market-report-2019-658153