05-Oct-2020 | Market Research Store
The University of Leeds researchers have recently created a new and rapid method for diagnosing diseases in patients. The researchers developed a system that keenly monitors every molecule in an individual to identify the presence of any kind of abnormality or disease in blood. By molecules, the researcher mean biomarkers, which are present in billions in the blood and specific diseases are found to have particular biomarkers spiked up. The new system has already proved positive in detecting a protein associated with cystic fibrosis. The results can be compiled using a few biomarkers and that too within a few minutes. Additionally, it is anticipated that the new system could accelerate coronavirus testing that too with accurate results.
The requirement of few drops of sample is likely to turn it into a highly preferred and reliable system. Moreover, the isolation of individual molecules from the samples for spotting specific disease is completed within a few minutes. DNA origami is the technique used in the new method to study the different shapes of DNA through its unique folding. The shapes of the DNA help find biomarkers that are the signals for identifying particular diseases. The nanopores are later used to read the one captured biomarker at a time. Thus, the combination of DNA origami and nanopores help quantitatively detect the disease biomarkers through single molecule sensitivity.
The technology is being transformed to identify a range of diseases such as COVID-19. The modification of DNA origami to detect COVID-19 molecules will help identify the protein that helps the coronavirus attack the human cells. Researchers have already found an inflammation marker called C-reactive protein to be the sole factor in regulating diseases such as cystic fibrosis. The sensitive detection of biomarkers is found to play an important role in disease diagnosis and management. This new technique will be the next miniaturized version of point-of-care detection.
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