15-Jan-2021 | Market Research Store

The University of California and the University of Michigan researchers have recently found an antibody that can inhibit the spread of the dengue virus within the body. This mosquito-borne pathogen is found to infect around 50–100 million people a year. The symptoms of dengue are fever, vomiting, muscle pain, and it can also lead to other severe illnesses or even death. Lately, there are no treatments or vaccines for treating the dengue virus. Additionally, as there are 4 diverse strains of the virus, there are chances of building up of antibodies against single strain and this can leave the patient vulnerable to the infections caused by other strains. It is this reason that no effective therapeutic has been discovered yet. Furthermore, Advanced Photon Source (APS) used by the scientists have proved to be a success.

The virus is found to use a specific protein named Non-Structural Protein 1 (NS1) for latching on to the protective cells around organs. These viruses then break the protective barrier such that the viruses invade into the cell and cause the rupturing of blood vessels. The researchers thus used the 2B7antibody to physically block the NS1 protein and thereby, prevent it from attaching to the cells. The blocking thus lowered the spread of the virus. The antibody is considered to be effective against all four strains of the dengue virus as it does not attack the virus directly and instead attacks the protein.

The structure of the NS1 protein attached with antibody (2B7) studied using the X-ray diffraction techniques in order to outline the way the antibody provides protection against the virus. The antibody’s efficiency in halting the spread of different strains of dengue virus is believed to provide new results for the development of potentially effective treatments against other flaviviruses like dengue, Zika, and West Nile.

The global dengue virus diagnostic test market published by Market Research Store comprises of all the changing market competitive dynamics coupled with the statistical figures that illuminates the expected market growth rate during the forecast period.