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Anca Vasculitis - Pipeline Review, H2 2014

Published: Dec-2014 | Format: PDF | Global Markets Direct | Number of pages: 54 | Code: MRS - 18562


Global Markets Directs, Anca Vasculitis Pipeline Review, H2 2014, provides an overview of the Anca Vasculitiss therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Anca Vasculitis, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Anca Vasculitis and special features on late-stage and discontinued projects.

Global Markets Directs report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Directs proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Directs team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Scope

The report provides a snapshot of the global therapeutic landscape of Anca Vasculitis
The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities
The report reviews key players involved in the therapeutics development for Anca Vasculitis and enlists all their major and minor projects
The report summarizes all the dormant and discontinued pipeline projects
A review of the Anca Vasculitis products under development by companies and universities/research institutes based on information derived from company and industry-specific sources
Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages
A detailed assessment of monotherapy and combination therapy pipeline projects
Coverage of the Anca Vasculitis pipeline on the basis of target, MoA, route of administration and molecule type
Latest news and deals relating related to pipeline products

Reasons to buy

Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies
Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
Develop strategic initiatives by understanding the focus areas of leading companies
Identify and understand important and diverse types of therapeutics under development for Anca Vasculitis
Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline
Devise corrective measures for pipeline projects by understanding Anca Vasculitis pipeline depth and focus of Indication therapeutics
Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

Table Of Content 

Table of Contents 2
List of Tables 4
List of Figures 4

Introduction 5
Global Markets Direct Report Coverage 5
Anca Vasculitis Overview 6
Therapeutics Development 7
Pipeline Products for Anca Vasculitis - Overview 7
Pipeline Products for Anca Vasculitis - Comparative Analysis 8
Anca Vasculitis - Therapeutics under Development by Companies 9
Anca Vasculitis - Pipeline Products Glance 10
Late Stage Products 10
Clinical Stage Products 11
Early Stage Products 12
Anca Vasculitis - Products under Development by Companies 13
Anca Vasculitis - Companies Involved in Therapeutics Development 14
Anthera Pharmaceuticals Inc. 14
ChemoCentryx, Inc. 15
GlaxoSmithKline plc 16
Anca Vasculitis - Therapeutics Assessment 17
Assessment by Monotherapy Products 17
Assessment by Target 18
Assessment by Mechanism of Action 20
Assessment by Route of Administration 22
Assessment by Molecule Type 24
Drug Profiles 26
belimumab - Drug Profile 26
Product Description 26
Mechanism of Action 26
R&D Progress 26
blisibimod - Drug Profile 29
Product Description 29
Mechanism of Action 29
R&D Progress 29
CCX-1378 - Drug Profile 32
Product Description 32
Mechanism of Action 32
R&D Progress 32
CCX-1641 - Drug Profile 33
Product Description 33
Mechanism of Action 33
R&D Progress 33
CCX-168 - Drug Profile 34
Product Description 34
Mechanism of Action 34
R&D Progress 34
mepolizumab - Drug Profile 36
Product Description 36
Mechanism of Action 36
R&D Progress 36
Anca Vasculitis - Recent Pipeline Updates 38
Anca Vasculitis - Product Development Milestones 48
Featured News & Press Releases 48
Nov 17, 2014: ChemoCentryx's Orally Administered C5aR Inhibitor CCX168 Shows Benefit In Non-Renal ANCA Vasculitis Disease Activity, In Addition To Previously Shown Kidney Disease Improvements 48
Jun 02, 2014: ChemoCentryx's Orally-Administered Complement 5a Receptor Inhibitor, CCX168, Shows Benefit in ANCA-Associated Vasculitis Based on Birmingham Vasculitis Activity Score and Renal Disease Measurements 49
Dec 03, 2013: ChemoCentryx Announces Positive Top-Line CCX168 Phase II Data in ANCA-Associated Renal Vasculitis 50
Nov 10, 2010: ChemoCentryx Presents Positive Phase I Results For CCX168 At Annual American College Of Rheumatology Meeting 51

Appendix 53
Methodology 53
Coverage 53
Secondary Research 53
Primary Research 53
Expert Panel Validation 53
Contact Us 54
Disclaimer 54

List of Tables

Number of Products under Development for Anca Vasculitis, H2 2014 7
Number of Products under Development for Anca Vasculitis - Comparative Analysis, H2 2014 8
Number of Products under Development by Companies, H2 2014 9
Comparative Analysis by Late Stage Development, H2 2014 10
Comparative Analysis by Clinical Stage Development, H2 2014 11
Comparative Analysis by Early Stage Development, H2 2014 12
Products under Development by Companies, H2 2014 13
Anca Vasculitis - Pipeline by Anthera Pharmaceuticals Inc., H2 2014 14
Anca Vasculitis - Pipeline by ChemoCentryx, Inc., H2 2014 15
Anca Vasculitis - Pipeline by GlaxoSmithKline plc, H2 2014 16
Assessment by Monotherapy Products, H2 2014 17
Number of Products by Stage and Target, H2 2014 19
Number of Products by Stage and Mechanism of Action, H2 2014 21
Number of Products by Stage and Route of Administration, H2 2014 23
Number of Products by Stage and Molecule Type, H2 2014 25
Anca Vasculitis Therapeutics - Recent Pipeline Updates, H2 2014 38

List of Figures

Number of Products under Development for Anca Vasculitis, H2 2014 7
Number of Products under Development for Anca Vasculitis - Comparative Analysis, H2 2014 8
Number of Products under Development by Companies, H2 2014 9
Assessment by Monotherapy Products, H2 2014 17
Number of Products by Top 10 Targets, H2 2014 18
Number of Products by Stage and Top 10 Targets, H2 2014 18
Number of Products by Top 10 Mechanism of Actions, H2 2014 20
Number of Products by Stage and Top 10 Mechanism of Actions, H2 2014 20
Number of Products by Top 10 Routes of Administration, H2 2014 22
Number of Products by Stage and Top 10 Routes of Administration, H2 2014 22
Number of Products by Top 10 Molecule Types, H2 2014 24
Number of Products by Stage and Top 10 Molecule Types, H2 2014 24

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