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Cognitive Impairment Associated With Schizophrenia (CIAS) - Pipeline Review, H1 2015

Published: Jan-2015 | Format: PDF | Global Markets Direct | Number of pages: 96 | Code: MRS - 18408


Global Markets Direct’s, ‘Cognitive Impairment Associated With Schizophrenia (CIAS) Pipeline Review, H1 2015’, provides an overview of the Cognitive Impairment Associated With Schizophrenia (CIAS)’s therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Cognitive Impairment Associated With Schizophrenia (CIAS), complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Cognitive Impairment Associated With Schizophrenia (CIAS) and special features on late-stage and discontinued projects.

Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct’s team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Scope

The report provides a snapshot of the global therapeutic landscape of Cognitive Impairment Associated With Schizophrenia (CIAS)
The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities 
The report reviews key players involved in the therapeutics development for Cognitive Impairment Associated With Schizophrenia (CIAS) and enlists all their major and minor projects
The report summarizes all the dormant and discontinued pipeline projects 
A review of the Cognitive Impairment Associated With Schizophrenia (CIAS) products under development by companies and universities/research institutes based on information derived from company and industry-specific sources
Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages
A detailed assessment of monotherapy and combination therapy pipeline projects
Coverage of the Cognitive Impairment Associated With Schizophrenia (CIAS) pipeline on the basis of target, MoA, route of administration and molecule type
Latest news and deals relating related to pipeline products

Reasons to buy

Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies
Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
Develop strategic initiatives by understanding the focus areas of leading companies
Identify and understand important and diverse types of therapeutics under development for Cognitive Impairment Associated With Schizophrenia (CIAS)
Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline
Devise corrective measures for pipeline projects by understanding Cognitive Impairment Associated With Schizophrenia (CIAS) pipeline depth and focus of Indication therapeutics
Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

Table Of Content

Table of Contents 2
List of Tables 6
List of Figures 7

Introduction 8
Global Markets Direct Report Coverage 8
Cognitive Impairment Associated With Schizophrenia (CIAS) Overview 9
Therapeutics Development 10
Pipeline Products for Cognitive Impairment Associated With Schizophrenia (CIAS) - Overview 10
Pipeline Products for Cognitive Impairment Associated With Schizophrenia (CIAS) - Comparative Analysis 11
Cognitive Impairment Associated With Schizophrenia (CIAS) - Therapeutics under Development by Companies 12
Cognitive Impairment Associated With Schizophrenia (CIAS) - Pipeline Products Glance 15
Late Stage Products 15
Clinical Stage Products 16
Early Stage Products 17
Cognitive Impairment Associated With Schizophrenia (CIAS) - Products under Development by Companies 18
Cognitive Impairment Associated With Schizophrenia (CIAS) - Companies Involved in Therapeutics Development 20
AbbVie Inc. 20
Amarantus Bioscience Holdings, Inc. 21
Avineuro Pharmaceuticals, Inc. 22
CoMentis, Inc. 23
Eli Lilly and Company 24
FORUM Pharmaceuticals Inc. 25
H. Lundbeck A/S 26
Intra-Cellular Therapies, Inc. 27
Iproteos S.L. 28
Merck & Co., Inc. 29
Mithridion, Inc. 30
Mnemosyne Pharmaceuticals, Inc. 31
Novartis AG 32
Pfizer Inc. 33
Saniona AB 34
Siena Biotech S.p.A. 35
SK Biopharmaceuticals Co., Ltd. 36
Sunovion Pharmaceuticals Inc. 37
Takeda Pharmaceutical Company Limited 38
Upsher-Smith Laboratories, Inc. 39
Cognitive Impairment Associated With Schizophrenia (CIAS) - Therapeutics Assessment 40
Assessment by Monotherapy Products 40
Assessment by Target 41
Assessment by Mechanism of Action 43
Assessment by Route of Administration 45
Assessment by Molecule Type 46
Drug Profiles 48
A-431404 - Drug Profile 48
Product Description 48
Mechanism of Action 48
R&D Progress 48
ABT-126 - Drug Profile 49
Product Description 49
Mechanism of Action 49
R&D Progress 49
AN-761 - Drug Profile 50
Product Description 50
Mechanism of Action 50
R&D Progress 50
AQW-051 - Drug Profile 51
Product Description 51
Mechanism of Action 51
R&D Progress 51
AUT-1 - Drug Profile 53
Product Description 53
Mechanism of Action 53
R&D Progress 53
AVL-3288 - Drug Profile 54
Product Description 54
Mechanism of Action 54
R&D Progress 54
AVN-211 - Drug Profile 55
Product Description 55
Mechanism of Action 55
R&D Progress 55
BNC-375 - Drug Profile 56
Product Description 56
Mechanism of Action 56
R&D Progress 56
CDD-0304 - Drug Profile 57
Product Description 57
Mechanism of Action 57
R&D Progress 57
DSP-3748 - Drug Profile 59
Product Description 59
Mechanism of Action 59
R&D Progress 59
eltoprazine - Drug Profile 60
Product Description 60
Mechanism of Action 60
R&D Progress 60
encenicline hydrochloride - Drug Profile 61
Product Description 61
Mechanism of Action 61
R&D Progress 61
erteberel - Drug Profile 64
Product Description 64
Mechanism of Action 64
R&D Progress 64
GTS-21 - Drug Profile 65
Product Description 65
Mechanism of Action 65
R&D Progress 65
IPR-001 - Drug Profile 67
Product Description 67
Mechanism of Action 67
R&D Progress 67
IPR-088 - Drug Profile 68
Product Description 68
Mechanism of Action 68
R&D Progress 68
ITI-214 - Drug Profile 69
Product Description 69
Mechanism of Action 69
R&D Progress 69
LUAF-64280 - Drug Profile 70
Product Description 70
Mechanism of Action 70
R&D Progress 70
PNU-120596 - Drug Profile 71
Product Description 71
Mechanism of Action 71
R&D Progress 71
roflumilast - Drug Profile 72
Product Description 72
Mechanism of Action 72
R&D Progress 72
SEN-15924 - Drug Profile 75
Product Description 75
Mechanism of Action 75
R&D Progress 75
SKL-15508 - Drug Profile 76
Product Description 76
Mechanism of Action 76
R&D Progress 76
Small Molecule to Agonize Neuronal Acetylcholine Receptor Subunit Alpha-7 for Central Nervous System - Drug Profile 77
Product Description 77
Mechanism of Action 77
R&D Progress 77
Small Molecule to Agonize NMDA2B for CIAS - Drug Profile 78
Product Description 78
Mechanism of Action 78
R&D Progress 78
Small Molecules for Cognitive Impairment Associated with Schizophrenia - Drug Profile 80
Product Description 80
Mechanism of Action 80
R&D Progress 80
TAK-058 - Drug Profile 81
Product Description 81
Mechanism of Action 81
R&D Progress 81
Cognitive Impairment Associated With Schizophrenia (CIAS) - Recent Pipeline Updates 82
Cognitive Impairment Associated With Schizophrenia (CIAS) - Dormant Projects 91
Cognitive Impairment Associated With Schizophrenia (CIAS) - Discontinued Products 93
Cognitive Impairment Associated With Schizophrenia (CIAS) - Product Development Milestones 94
Featured News & Press Releases 94
Apr 17, 2013: SK Biopharma Announces FDA's Authorization Of IND For SKL15508 For Treatment Of Cognitive Impairment Associated With Schizophrenia 94
Feb 19, 2013: Intra-Cellular Therapies Completes Phase I Single Rising Dose Trial Of Selective Phosphodiesterase 1 Inhibitor 94
 

Appendix 95
Methodology 95
Coverage 95
Secondary Research 95
Primary Research 95
Expert Panel Validation 95
Contact Us 96
Disclaimer 96
 

List of Tables

Number of Products under Development for Cognitive Impairment Associated With Schizophrenia (CIAS), H1 2015 10
Number of Products under Development for Cognitive Impairment Associated With Schizophrenia (CIAS) - Comparative Analysis, H1 2015 11
Number of Products under Development by Companies, H1 2015 13
Number of Products under Development by Companies, H1 2015 (Contd..1) 14
Comparative Analysis by Late Stage Development, H1 2015 15
Comparative Analysis by Clinical Stage Development, H1 2015 16
Comparative Analysis by Early Stage Development, H1 2015 17
Products under Development by Companies, H1 2015 18
Products under Development by Companies, H1 2015 (Contd..1) 19
Cognitive Impairment Associated With Schizophrenia (CIAS) - Pipeline by AbbVie Inc., H1 2015 20
Cognitive Impairment Associated With Schizophrenia (CIAS) - Pipeline by Amarantus Bioscience Holdings, Inc., H1 2015 21
Cognitive Impairment Associated With Schizophrenia (CIAS) - Pipeline by Avineuro Pharmaceuticals, Inc., H1 2015 22
Cognitive Impairment Associated With Schizophrenia (CIAS) - Pipeline by CoMentis, Inc., H1 2015 23
Cognitive Impairment Associated With Schizophrenia (CIAS) - Pipeline by Eli Lilly and Company, H1 2015 24
Cognitive Impairment Associated With Schizophrenia (CIAS) - Pipeline by FORUM Pharmaceuticals Inc., H1 2015 25
Cognitive Impairment Associated With Schizophrenia (CIAS) - Pipeline by H. Lundbeck A/S, H1 2015 26
Cognitive Impairment Associated With Schizophrenia (CIAS) - Pipeline by Intra-Cellular Therapies, Inc., H1 2015 27
Cognitive Impairment Associated With Schizophrenia (CIAS) - Pipeline by Iproteos S.L., H1 2015 28
Cognitive Impairment Associated With Schizophrenia (CIAS) - Pipeline by Merck & Co., Inc., H1 2015 29
Cognitive Impairment Associated With Schizophrenia (CIAS) - Pipeline by Mithridion, Inc., H1 2015 30
Cognitive Impairment Associated With Schizophrenia (CIAS) - Pipeline by Mnemosyne Pharmaceuticals, Inc., H1 2015 31
Cognitive Impairment Associated With Schizophrenia (CIAS) - Pipeline by Novartis AG, H1 2015 32
Cognitive Impairment Associated With Schizophrenia (CIAS) - Pipeline by Pfizer Inc., H1 2015 33
Cognitive Impairment Associated With Schizophrenia (CIAS) - Pipeline by Saniona AB, H1 2015 34
Cognitive Impairment Associated With Schizophrenia (CIAS) - Pipeline by Siena Biotech S.p.A., H1 2015 35
Cognitive Impairment Associated With Schizophrenia (CIAS) - Pipeline by SK Biopharmaceuticals Co., Ltd., H1 2015 36
Cognitive Impairment Associated With Schizophrenia (CIAS) - Pipeline by Sunovion Pharmaceuticals Inc., H1 2015 37
Cognitive Impairment Associated With Schizophrenia (CIAS) - Pipeline by Takeda Pharmaceutical Company Limited, H1 2015 38
Cognitive Impairment Associated With Schizophrenia (CIAS) - Pipeline by Upsher-Smith Laboratories, Inc., H1 2015 39
Assessment by Monotherapy Products, H1 2015 40
Number of Products by Stage and Target, H1 2015 42
Number of Products by Stage and Mechanism of Action, H1 2015 44
Number of Products by Stage and Route of Administration, H1 2015 45
Number of Products by Stage and Molecule Type, H1 2015 47
Cognitive Impairment Associated With Schizophrenia (CIAS) Therapeutics - Recent Pipeline Updates, H1 2015 82
Cognitive Impairment Associated With Schizophrenia (CIAS) - Dormant Projects, H1 2015 91
Cognitive Impairment Associated With Schizophrenia (CIAS) - Dormant Projects (Contd..1), H1 2015 92
Cognitive Impairment Associated With Schizophrenia (CIAS) - Discontinued Products, H1 2015 93

List of Figures

Number of Products under Development for Cognitive Impairment Associated With Schizophrenia (CIAS), H1 2015 10
Number of Products under Development for Cognitive Impairment Associated With Schizophrenia (CIAS) - Comparative Analysis, H1 2015 11
Number of Products under Development by Companies, H1 2015 12
Comparative Analysis by Clinical Stage Development, H1 2015 16
Comparative Analysis by Early Stage Products, H1 2015 17
Assessment by Monotherapy Products, H1 2015 40
Number of Products by Top 10 Targets, H1 2015 41
Number of Products by Stage and Top 10 Targets, H1 2015 42
Number of Products by Top 10 Mechanism of Actions, H1 2015 43
Number of Products by Stage and Top 10 Mechanism of Actions, H1 2015 44
Number of Products by Stage and Top 10 Routes of Administration, H1 2015 45
Number of Products by Top 10 Molecule Types, H1 2015 46
Number of Products by Stage and Top 10 Molecule Types, H1 2015 47

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