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Dilated Cardiomyopathy - Pipeline Review, H1 2015

Published: Jan-2015 | Format: PDF | Global Markets Direct | Number of pages: 56 | Code: MRS - 18146


Global Markets Directs, Dilated Cardiomyopathy Pipeline Review, H1 2015, provides an overview of the Dilated Cardiomyopathys therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Dilated Cardiomyopathy, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Dilated Cardiomyopathy and special features on late-stage and discontinued projects.

Global Markets Directs report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Directs proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Directs team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Scope

The report provides a snapshot of the global therapeutic landscape of Dilated Cardiomyopathy
The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities
The report reviews key players involved in the therapeutics development for Dilated Cardiomyopathy and enlists all their major and minor projects
The report summarizes all the dormant and discontinued pipeline projects 
A review of the Dilated Cardiomyopathy products under development by companies and universities/research institutes based on information derived from company and industry-specific sources
Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages
A detailed assessment of monotherapy and combination therapy pipeline projects
Coverage of the Dilated Cardiomyopathy pipeline on the basis of target, MoA, route of administration and molecule type
Latest news and deals relating related to pipeline products

Reasons to buy

Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies
Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
Develop strategic initiatives by understanding the focus areas of leading companies
Identify and understand important and diverse types of therapeutics under development for Dilated Cardiomyopathy
Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline
Devise corrective measures for pipeline projects by understanding Dilated Cardiomyopathy pipeline depth and focus of Indication therapeutics
Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

Table Of Content

Table of Contents 2
List of Tables 4
List of Figures 4

Introduction 5
Global Markets Direct Report Coverage 5
Dilated Cardiomyopathy Overview 6
Therapeutics Development 7
Pipeline Products for Dilated Cardiomyopathy - Overview 7
Pipeline Products for Dilated Cardiomyopathy - Comparative Analysis 8
Dilated Cardiomyopathy - Therapeutics under Development by Companies 9
Dilated Cardiomyopathy - Pipeline Products Glance 10
Clinical Stage Products 10
Early Stage Products 11
Dilated Cardiomyopathy - Products under Development by Companies 12
Dilated Cardiomyopathy - Companies Involved in Therapeutics Development 13
Array BioPharma Inc. 13
Kasiak Research Pvt. Ltd. 14
Sanofi 15
Vericel Corporation 16
Zensun (Shanghai) Sci & Tech Co., Ltd. 17
Dilated Cardiomyopathy - Therapeutics Assessment 18
Assessment by Monotherapy Products 18
Assessment by Target 19
Assessment by Mechanism of Action 21
Assessment by Route of Administration 23
Assessment by Molecule Type 25
Drug Profiles 27
ARRY-797 - Drug Profile 27
Product Description 27
Mechanism of Action 27
R&D Progress 27
CAP-1002 - Drug Profile 29
Product Description 29
Mechanism of Action 29
R&D Progress 29
ixmyelocel-T - Drug Profile 31
Product Description 31
Mechanism of Action 31
R&D Progress 31
Neucardin - Drug Profile 34
Product Description 34
Mechanism of Action 34
R&D Progress 34
Refacell-DCM - Drug Profile 37
Product Description 37
Mechanism of Action 37
R&D Progress 37
Small Molecule for Dilated Cardiomyopathy - Drug Profile 38
Product Description 38
Mechanism of Action 38
R&D Progress 38
Dilated Cardiomyopathy - Recent Pipeline Updates 39
Dilated Cardiomyopathy - Dormant Projects 48
Dilated Cardiomyopathy - Product Development Milestones 49
Featured News & Press Releases 49
Dec 19, 2013: Aastrom Biosciences Granted Composition-of-Matter Patent for Ixmyelocel-T in Australia 49
Dec 17, 2013: Capricor Therapeutics Cleared to Begin Phase II Portion of ALLSTAR Clinical Trial with CAP-1002 in Patients Following Heart Attack 49
Apr 19, 2013: Aastrom Biosciences Announces First Patients Treated In IxCELL-DCM Clinical Study Of Ixmyelocel-T 50
Jun 06, 2012: Aastrom Presents Preclinical Data Of Ixmyelocel-T At 18th Annual International Society For Cellular Therapy Meeting 50
May 10, 2012: Treatment With Ixmyelocel-T Shows Improvement In Outcome Of Heart Failure Patients 51
May 07, 2012: Aastrom To Present Phase IIa Trial Results Of Ixmyelocel-T In Dilated Cardiomyopathy Patients At SCAI Scientific Sessions 52
Oct 03, 2011: Aastrom Receives European Composition-Of-Matter Patent For Ixmyelocel-T 52
Sep 19, 2011: Aastrom Announces Positive 12-Month Safety And Efficacy Data From IMPACT-DCM Phase II Clinical Trial For Ixmyelocel-T In Treatment Of Dilated Cardiomyopathy 53
Sep 14, 2011: Aastrom To Present 12-Month Data From IMPACT-DCM Phase II Clinical Trial For Ixmyelocel-T In Treatment Of Dilated Cardiomyopathy 54
May 17, 2011: Aastrom To Present Results From Two Studies of Ixmyelocel-T At International Society For Cellular Therapy Meeting 54

Appendix 55
Methodology 55
Coverage 55
Secondary Research 55
Primary Research 55
Expert Panel Validation 55
Contact Us 55
Disclaimer 56

List of Tables

Number of Products under Development for Dilated Cardiomyopathy, H1 2015 7
Number of Products under Development for Dilated Cardiomyopathy - Comparative Analysis, H1 2015 8
Number of Products under Development by Companies, H1 2015 9
Comparative Analysis by Clinical Stage Development, H1 2015 10
Comparative Analysis by Early Stage Development, H1 2015 11
Products under Development by Companies, H1 2015 12
Dilated Cardiomyopathy - Pipeline by Array BioPharma Inc., H1 2015 13
Dilated Cardiomyopathy - Pipeline by Kasiak Research Pvt. Ltd., H1 2015 14
Dilated Cardiomyopathy - Pipeline by Sanofi, H1 2015 15
Dilated Cardiomyopathy - Pipeline by Vericel Corporation, H1 2015 16
Dilated Cardiomyopathy - Pipeline by Zensun (Shanghai) Sci & Tech Co., Ltd., H1 2015 17
Assessment by Monotherapy Products, H1 2015 18
Number of Products by Stage and Target, H1 2015 20
Number of Products by Stage and Mechanism of Action, H1 2015 22
Number of Products by Stage and Route of Administration, H1 2015 24
Number of Products by Stage and Molecule Type, H1 2015 26
Dilated Cardiomyopathy Therapeutics - Recent Pipeline Updates, H1 2015 39
Dilated Cardiomyopathy - Dormant Projects, H1 2015 48

List of Figures

Number of Products under Development for Dilated Cardiomyopathy, H1 2015 7
Number of Products under Development for Dilated Cardiomyopathy - Comparative Analysis, H1 2015 8
Number of Products under Development by Companies, H1 2015 9
Comparative Analysis by Clinical Stage Development, H1 2015 10
Comparative Analysis by Early Stage Products, H1 2015 11
Assessment by Monotherapy Products, H1 2015 18
Number of Products by Top 10 Targets, H1 2015 19
Number of Products by Stage and Top 10 Targets, H1 2015 19
Number of Products by Top 10 Mechanism of Actions, H1 2015 21
Number of Products by Stage and Top 10 Mechanism of Actions, H1 2015 21
Number of Products by Top 10 Routes of Administration, H1 2015 23
Number of Products by Stage and Top 10 Routes of Administration, H1 2015 23
Number of Products by Top 10 Molecule Types, H1 2015 25
Number of Products by Stage and Top 10 Molecule Types, H1 2015 25

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