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Hypercholesterolemia Global Clinical Trials Review, H1, 2014

Published: Apr-2014 | Format: PDF | GlobalData | Number of pages: 202 | Code: MRS - 24133


GlobalData's clinical trial report, "Hypercholesterolemia Global Clinical Trials Review, H1, 2014" provides data on the Hypercholesterolemia clinical trial scenario. This report provides elemental information and data relating to the clinical trials on Hypercholesterolemia. It includes an overview of the trial numbers and their recruitment status as per the site of trial conduction across the globe. The databook offers a preliminary coverage of disease clinical trials by their phase, trial status, prominence of the sponsors and also provides briefing pertaining to the number of trials for the key drugs for treating Hypercholesterolemia. This report is built using data and information sourced from proprietary databases, primary and secondary research and in-house analysis by GlobalData's team of industry experts.

Scope

  • Data on the number of clinical trials conducted in North America, South and Central America, Europe, Middle-East and Africa and Asia-pacific and top five national contributions in each, along with the clinical trial scenario in BRIC nations
  • Clinical trial (complete and in progress) data by phase, trial status, subjects recruited and sponsor type
  • Listings of discontinued trials (suspended, withdrawn and terminated)

Reasons to buy

  • Understand the dynamics of a particular indication in a condensed manner
  • Abridged view of the performance of the trials in terms of their status, recruitment, location, sponsor type and many more
  • Obtain discontinued trial listing for trials across the globe
  • Espy the commercial landscape of the major Universities / Institutes / Hospitals or Companies

Table of Contents

Table of Contents 2
List of Tables 4
List of Figures 5
Introduction 6
Hypercholesterolemia 6
Report Guidance 6
Clinical Trials by Region 7
Clinical Trials and Average Enrollment by Country 8
Top Five Countries Contributing to Clinical Trials in Asia-Pacific 10
Top Five Countries Contributing to Clinical Trials in Europe 11
Top Countries Contributing to Clinical Trials in North America 12
Top Five Countries Contributing to Clinical Trials in Middle East and Africa 13
Top Five Countries Contributing to Clinical Trials in Central and South America 14
Clinical Trials by G7 Countries: Proportion of Hypercholesterolemia to Metabolic Disorders Clinical Trials 15
Clinical Trials by Phase in G7 Countries 16
Clinical Trials in G7 Countries by Trial Status 17
Clinical Trials by E7 Countries: Proportion of Hypercholesterolemia to Metabolic Disorders Clinical Trials 18
Clinical Trials by Phase in E7 Countries 19
Clinical Trials in E7 Countries by Trial Status 20
Clinical Trials by Phase 21
In Progress Trials by Phase 22
Clinical Trials by Trial Status 23
Clinical Trials by End Point Status 24
Unaccomplished Trials of Hypercholesterolemia 25
Subjects Recruited Over a Period of Time 32
Clinical Trials by Sponsor Type 33
Prominent Sponsors 34
Top Companies Participating in Hypercholesterolemia Therapeutics Clinical Trials 35
Prominent Drugs 37
Latest Clinical Trials News on Hypercholesterolemia 38
Apr 01, 2014: Sanofi and Regeneron Report Positive Results With Alirocumab From Phase 2 Japanese Study 38
Mar 30, 2014: Data From Phase 3 Pivotal Studies Show Amgen's Novel Investigational Cholesterol-Lowering Medication Evolocumab Significantly Reduced LDL Cholesterol In Statin Intolerant Patients And In Patients On Statins 38
Mar 30, 2014: Evolocumab safely drops LDL cholesterol well below statin-only baseline 41
Mar 29, 2014: New Detailed Data from Three Phase 3 Pivotal Studies Show Amgen's Novel Investigational Cholesterol-Lowering Medicine Evolocumab Significantly Reduced LDL Cholesterol By 55-66 Percent Compared To Placebo In Patients With High Cholesterol 42
Dec 19, 2013: Amgen Announces Positive Top-Line Results From 52-Week Phase 3 DESCARTES Study Of Evolocumab In Patients With High Cholesterol 44
Clinical Trial Profiles 46
Clinical Trial Overview of Top Companies 46
Merck & Co., Inc. 46
Clinical Trial Overview of Merck & Co., Inc. 46
AstraZeneca PLC 56
Clinical Trial Overview of AstraZeneca PLC 56
Sanofi 64
Clinical Trial Overview of Sanofi 64
Pfizer Inc. 69
Clinical Trial Overview of Pfizer Inc. 69
Regeneron Pharmaceuticals, Inc. 72
Clinical Trial Overview of Regeneron Pharmaceuticals, Inc. 72
Aegerion Pharmaceuticals, Inc. 75
Clinical Trial Overview of Aegerion Pharmaceuticals, Inc. 75
Novartis AG 77
Clinical Trial Overview of Novartis AG 77
Kowa Company, Ltd. 79
Clinical Trial Overview of Kowa Company, Ltd. 79
Isis Pharmaceuticals, Inc. 81
Clinical Trial Overview of Isis Pharmaceuticals, Inc. 81
Amgen Inc. 83
Clinical Trial Overview of Amgen Inc. 83
Clinical Trial Overview of Top Institutes / Government 85
National Heart, Lung, and Blood Institute 85
Clinical Trial Overview of National Heart, Lung, and Blood Institute 85
University of Manitoba 87
Clinical Trial Overview of University of Manitoba 87
Gachon University Gil Hospital 88
Clinical Trial Overview of Gachon University Gil Hospital 88
University of Pennsylvania 89
Clinical Trial Overview of University of Pennsylvania 89
University of Toronto 90
Clinical Trial Overview of University of Toronto 90
Osaka University 91
Clinical Trial Overview of Osaka University 91
University of Jena 92
Clinical Trial Overview of University of Jena 92
Maastricht University Medical Center 93
Clinical Trial Overview of Maastricht University Medical Center 93
Washington University School of Medicine 94
Clinical Trial Overview of Washington University School of Medicine 94
Monash University 95
Clinical Trial Overview of Monash University 95
Five Key Clinical Profiles 96
Appendix 200
Abbreviations 200
Definitions 200
Research Methodology 201
Secondary Research 201
About GlobalData 202
Contact Us 202
Disclaimer 202
Source 202

List of Tables

Hypercholesterolemia Therapeutics, Global, Clinical Trials by Region, 2014* 7
Hypercholesterolemia Therapeutics, Global, Clinical Trials and Average Enrollment by Top Countries, 2014* 8
Hypercholesterolemia Therapeutics, Global, Clinical Trials In Progress by Top Countries, 2014* 9
Hypercholesterolemia Therapeutics Clinical Trials, Asia-Pacific, Top Five Countries, 2014* 10
Hypercholesterolemia Therapeutics Clinical Trials, Europe, Top Five Countries, 2014* 11
Hypercholesterolemia Therapeutics Clinical Trials, North America, Top Countries, 2014* 12
Hypercholesterolemia Therapeutics Clinical Trials, Middle East and Africa, Top Five Countries, 2014* 13
Hypercholesterolemia Therapeutics Clinical Trials, Central and South America, Top Five Countries, 2014* 14
Proportion of Hypercholesterolemia to Metabolic Disorders Clinical Trials, G7 Countries (%), 2014* 15
Hypercholesterolemia Therapeutics, G7 Countries, Clinical Trials by Phase, 2014* 16
Hypercholesterolemia Therapeutics, G7 Countries, Clinical Trials by Trial Status, 2014* 17
Proportion of Hypercholesterolemia to Metabolic Disorders Clinical Trials, E7 Countries (%), 2014* 18
Hypercholesterolemia Therapeutics, E7 Countries, Clinical Trials by Phase, 2014* 19
Hypercholesterolemia Therapeutics, E7 Countries, Clinical Trials by Trial Status, 2014* 20
Hypercholesterolemia Therapeutics, Global, Clinical Trials by Phase, 2014* 21
Hypercholesterolemia Therapeutics, Global, Clinical Trials In Progress by Phase 2014* 22
Hypercholesterolemia Therapeutics, Global, Clinical Trials by Trial Status, 2014* 23
Hypercholesterolemia Therapeutics Clinical Trials, Global, by End Point Status, 2014* 24
Hypercholesterolemia Therapeutics, Global, Suspended Clinical Trials, 2014* 25
Hypercholesterolemia Therapeutics, Global, Withdrawn Clinical Trials, 2014* 26
Hypercholesterolemia Therapeutics, Global, Terminated Clinical Trials, 2014* 27
Hypercholesterolemia Therapeutics Clinical Trials, Global, Average Enrollment Target Trends, 2009-2013 32
Hypercholesterolemia Therapeutics Market, Global, Clinical Trials by Sponsor Type, 2014* 33
Hypercholesterolemia Therapeutics Clinical Trials, Global, Key Sponsors, 2014* 34
Hypercholesterolemia Therapeutics Clinical Trials, Global, Top Companies by Phase, 2014* 36
Hypercholesterolemia Therapeutics Clinical Trials, Global, Ongoing Clinical Trials by Prominent Drugs, 2014* 37
Hypercholesterolemia Therapeutics Clinical Trials Market, Global, Clinical Trials by Merck & Co., Inc., 2014* 46
Hypercholesterolemia Therapeutics Clinical Trials Market, Global, Clinical Trials by AstraZeneca PLC, 2014* 56
Hypercholesterolemia Therapeutics Clinical Trials Market, Global, Clinical Trials by Sanofi, 2014* 64
Hypercholesterolemia Therapeutics Clinical Trials Market, Global, Clinical Trials by Pfizer Inc., 2014* 69
Hypercholesterolemia Therapeutics Clinical Trials Market, Global, Clinical Trials by Regeneron Pharmaceuticals, Inc., 2014* 72
Hypercholesterolemia Therapeutics Clinical Trials Market, Global, Clinical Trials by Aegerion Pharmaceuticals, Inc., 2014* 75
Hypercholesterolemia Therapeutics Clinical Trials Market, Global, Clinical Trials by Novartis AG, 2014* 77
Hypercholesterolemia Therapeutics Clinical Trials Market, Global, Clinical Trials by Kowa Company, Ltd., 2014* 79
Hypercholesterolemia Therapeutics Clinical Trials Market, Global, Clinical Trials by Isis Pharmaceuticals, Inc., 2014* 81
Hypercholesterolemia Therapeutics Clinical Trials Market, Global, Clinical Trials by Amgen Inc., 2014* 83
Hypercholesterolemia Therapeutics Clinical Trials Market, Global, Clinical Trials by National Heart, Lung, and Blood Institute, 2014* 85
Hypercholesterolemia Therapeutics Clinical Trials Market, Global, Clinical Trials by University of Manitoba, 2014* 87
Hypercholesterolemia Therapeutics Clinical Trials Market, Global, Clinical Trials by Gachon University Gil Hospital, 2014* 88
Hypercholesterolemia Therapeutics Clinical Trials Market, Global, Clinical Trials by University of Pennsylvania, 2014* 89
Hypercholesterolemia Therapeutics Clinical Trials Market, Global, Clinical Trials by University of Toronto, 2014* 90
Hypercholesterolemia Therapeutics Clinical Trials Market, Global, Clinical Trials by Osaka University, 2014* 91
Hypercholesterolemia Therapeutics Clinical Trials Market, Global, Clinical Trials by University of Jena, 2014* 92
Hypercholesterolemia Therapeutics Clinical Trials Market, Global, Clinical Trials by Maastricht University Medical Center, 2014* 93
Hypercholesterolemia Therapeutics Clinical Trials Market, Global, Clinical Trials by Washington University School of Medicine, 2014* 94
Hypercholesterolemia Therapeutics Clinical Trials Market, Global, Clinical Trials by Monash University, 2014* 95

List of Figures

Hypercholesterolemia Therapeutics, Global, Clinical Trials by Region (%), 2014* 7
Hypercholesterolemia Therapeutics, Global, Clinical Trials and Average Enrollment by Top Countries, 2014* 8
Hypercholesterolemia Therapeutics, Global, Clinical Trials In Progress by Top Countries, 2014* 9
Hypercholesterolemia Therapeutics Clinical Trials, Asia-Pacific, Top Five Countries (%), 2014* 10
Hypercholesterolemia Therapeutics Clinical Trials, Europe, Top Five Countries (%), 2014* 11
Hypercholesterolemia Therapeutics Clinical Trials, North America, Top Countries (%), 2014* 12
Hypercholesterolemia Therapeutics Clinical Trials, Middle East and Africa, Top Five Countries (%), 2014* 13
Hypercholesterolemia Therapeutics Clinical Trials, Central and South America, Top Five Countries (%), 2014* 14
Proportion of Hypercholesterolemia to Metabolic Disorders Clinical Trials, G7 Countries (%), 2014* 15
Hypercholesterolemia Therapeutics, G7 Countries, Clinical Trials by Phase, 2014* 16
Hypercholesterolemia Therapeutics, G7 Countries, Clinical Trials by Trial Status, 2014* 17
Proportion of Hypercholesterolemia to Metabolic Disorders Clinical Trials, E7 Countries (%), 2014* 18
Hypercholesterolemia Therapeutics, E7 Countries, Clinical Trials by Phase, 2014* 19
Hypercholesterolemia Therapeutics, E7 Countries, Clinical Trials by Trial Status, 2014* 20
Hypercholesterolemia Therapeutics, Global, Clinical Trials by Phase (%), 2014* 21
Hypercholesterolemia Therapeutics, Global, Clinical Trials In Progress by Phase, 2014* 22
Hypercholesterolemia Therapeutics, Global, Clinical Trials by Trial Status, 2014* 23
Hypercholesterolemia Therapeutics Clinical Trials, Global, by End Point Status, 2014* 24
Hypercholesterolemia Therapeutics Clinical Trials, Global, Average Enrollment Target Trends, 2009-2013 32
Hypercholesterolemia Therapeutics Market, Global, Clinical Trials by Sponsor Type (%), 2014* 33
Hypercholesterolemia Therapeutics Clinical Trials, Global, Key Sponsors, 2014* 34
Hypercholesterolemia Therapeutics Clinical Trials, Global, Top Companies by Phase, 2014* 35
Hypercholesterolemia Therapeutics Clinical Trials, Global, Ongoing Clinical Trials by Prominent Drugs, 2014* 37
GlobalData Methodology 201

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