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Malignant Glioma - Pipeline Review, H2 2014

Published: Dec-2014 | Format: PDF | Global Markets Direct | Number of pages: 70 | Code: MRS - 2095

 

Global Markets Direct’s, ‘Malignant Glioma Pipeline Review, H2 2014’, provides an overview of the Malignant Glioma’s therapeutic pipeline.

 

This report provides comprehensive information on the therapeutic development for Malignant Glioma, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Malignant Glioma and special features on late-stage and discontinued projects.

 

Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct’s team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

 

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

 

Scope

 

The report provides a snapshot of the global therapeutic landscape of Malignant Glioma
The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities 
The report reviews key players involved in the therapeutics development for Malignant Glioma and enlists all their major and minor projects
The report summarizes all the dormant and discontinued pipeline projects 
A review of the Malignant Glioma products under development by companies and universities/research institutes based on information derived from company and industry-specific sources
Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages
A detailed assessment of monotherapy and combination therapy pipeline projects
Coverage of the Malignant Glioma pipeline on the basis of target, MoA, route of administration and molecule type
Latest news and deals relating related to pipeline products

 

Reasons to buy

 

Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies
Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
Develop strategic initiatives by understanding the focus areas of leading companies
Identify and understand important and diverse types of therapeutics under development for Malignant Glioma
Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline
Devise corrective measures for pipeline projects by understanding Malignant Glioma pipeline depth and focus of Indication therapeutics
Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

Table of Contents
 

Table of Contents 2
List of Tables 5
List of Figures 5
Introduction 6
Global Markets Direct Report Coverage 6
Malignant Glioma Overview 7
Therapeutics Development 8
Pipeline Products for Malignant Glioma - Overview 8
Pipeline Products for Malignant Glioma - Comparative Analysis 9
Malignant Glioma - Therapeutics under Development by Companies 10
Malignant Glioma - Therapeutics under Investigation by Universities/Institutes 11
Malignant Glioma - Pipeline Products Glance 12
Late Stage Products 12
Clinical Stage Products 13
Early Stage Products 14
Malignant Glioma - Products under Development by Companies 15
Malignant Glioma - Products under Investigation by Universities/Institutes 16
Malignant Glioma - Companies Involved in Therapeutics Development 17
Advantagene, Inc. 17
Eli Lilly and Company 18
Lipopharma Therapeutics SL 19
Nuo Therapeutics, Inc. 20
Orbus Therapeutics, Inc. 21
Sanofi 22
Stemline Therapeutics, Inc. 23
ZIOPHARM Oncology, Inc. 24
Malignant Glioma - Therapeutics Assessment 25
Assessment by Monotherapy Products 25
Assessment by Target 26
Assessment by Mechanism of Action 28
Assessment by Route of Administration 30
Assessment by Molecule Type 32
Drug Profiles 34
Ac-929C - Drug Profile 34
Product Description 34
Mechanism of Action 34
R&D Progress 34
Ad-RTS-IL-12 - Drug Profile 35
Product Description 35
Mechanism of Action 35
R&D Progress 35
ALD-451 - Drug Profile 37
Product Description 37
Mechanism of Action 37
R&D Progress 37
Dendritic Cell Therapy for Malignant Gliomas - Drug Profile 38
Product Description 38
Mechanism of Action 38
R&D Progress 38
Dendritic Cell Therapy for Oncology - Drug Profile 39
Product Description 39
Mechanism of Action 39
R&D Progress 39
Dendritic Cell Therapy for Oncology - Drug Profile 41
Product Description 41
Mechanism of Action 41
R&D Progress 41
Dendritic Cell Therapy for Oncology - Drug Profile 42
Product Description 42
Mechanism of Action 42
R&D Progress 42
eflornithine hydrochloride - Drug Profile 43
Product Description 43
Mechanism of Action 43
R&D Progress 43
galunisertib - Drug Profile 45
Product Description 45
Mechanism of Action 45
R&D Progress 45
GliAtak - Drug Profile 47
Product Description 47
Mechanism of Action 47
R&D Progress 47
IDD-004 - Drug Profile 48
Product Description 48
Mechanism of Action 48
R&D Progress 48
LD-224 - Drug Profile 49
Product Description 49
Mechanism of Action 49
R&D Progress 49
Minerval - Drug Profile 51
Product Description 51
Mechanism of Action 51
R&D Progress 51
Oncolytic Virus for Oncology - Drug Profile 53
Product Description 53
Mechanism of Action 53
R&D Progress 53
SL-701 - Drug Profile 54
Product Description 54
Mechanism of Action 54
R&D Progress 54
Small Molecule for Brain Cancer and Malignant Glioma - Drug Profile 56
Product Description 56
Mechanism of Action 56
R&D Progress 56
Vaccine to Target Survivin for Malignant Glioma - Drug Profile 57
Product Description 57
Mechanism of Action 57
R&D Progress 57
voxtalisib - Drug Profile 58
Product Description 58
Mechanism of Action 58
R&D Progress 58
WT-1 Peptide Vaccine - Drug Profile 60
Product Description 60
Mechanism of Action 60
R&D Progress 60
Malignant Glioma - Recent Pipeline Updates 61
Malignant Glioma - Dormant Projects 67
Malignant Glioma - Discontinued Products 68

 

Appendix 69
Methodology 69
Coverage 69
Secondary Research 69
Primary Research 69
Expert Panel Validation 69
Contact Us 70
Disclaimer 70

 

List of Tables
 

Number of Products under Development for Malignant Glioma, H2 2014 8
Number of Products under Development for Malignant Glioma - Comparative Analysis, H2 2014 9
Number of Products under Development by Companies, H2 2014 10
Number of Products under Investigation by Universities/Institutes, H2 2014 11
Comparative Analysis by Late Stage Development, H2 2014 12
Comparative Analysis by Clinical Stage Development, H2 2014 13
Comparative Analysis by Early Stage Development, H2 2014 14
Products under Development by Companies, H2 2014 15
Products under Investigation by Universities/Institutes, H2 2014 16
Malignant Glioma - Pipeline by Advantagene, Inc., H2 2014 17
Malignant Glioma - Pipeline by Eli Lilly and Company, H2 2014 18
Malignant Glioma - Pipeline by Lipopharma Therapeutics SL, H2 2014 19
Malignant Glioma - Pipeline by Nuo Therapeutics, Inc., H2 2014 20
Malignant Glioma - Pipeline by Orbus Therapeutics, Inc., H2 2014 21
Malignant Glioma - Pipeline by Sanofi, H2 2014 22
Malignant Glioma - Pipeline by Stemline Therapeutics, Inc., H2 2014 23
Malignant Glioma - Pipeline by ZIOPHARM Oncology, Inc., H2 2014 24
Assessment by Monotherapy Products, H2 2014 25
Number of Products by Stage and Target, H2 2014 27
Number of Products by Stage and Mechanism of Action, H2 2014 29
Number of Products by Stage and Route of Administration, H2 2014 31
Number of Products by Stage and Molecule Type, H2 2014 33
Malignant Glioma Therapeutics - Recent Pipeline Updates, H2 2014 61
Malignant Glioma - Dormant Projects, H2 2014 67
Malignant Glioma - Discontinued Products, H2 2014 68"

 

List of Figures
 

Number of Products under Development for Malignant Glioma, H2 2014 8
Number of Products under Development for Malignant Glioma - Comparative Analysis, H2 2014 9
Number of Products under Development by Companies, H2 2014 10
Number of Products under Investigation by Universities/Institutes, H2 2014 11
Comparative Analysis by Clinical Stage Development, H2 2014 13
Comparative Analysis by Early Stage Products, H2 2014 14
Assessment by Monotherapy Products, H2 2014 25
Number of Products by Top 10 Targets, H2 2014 26
Number of Products by Stage and Top 10 Targets, H2 2014 27
Number of Products by Top 10 Mechanism of Actions, H2 2014 28
Number of Products by Stage and Top 10 Mechanism of Actions, H2 2014 29
Number of Products by Top 10 Routes of Administration, H2 2014 30
Number of Products by Stage and Top 10 Routes of Administration, H2 2014 31
Number of Products by Top 10 Molecule Types, H2 2014 32
Number of Products by Stage and Top 10 Molecule Types, H2 2014 33

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