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Plague - Pipeline Review, H2 2015

Published: Aug-2015 | Format: PDF | Global Markets Direct | Number of pages: 62 | Code: MRS - 35123

Plague - Pipeline Review, H2 2015

Summary

Global Markets Direct’s, ‘Plague - Pipeline Review, H2 2015’, provides an overview of the Plague’s therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Plague, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Plague and special features on late-stage and discontinued projects.

Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct’s team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

- The report provides a snapshot of the global therapeutic landscape of Plague
- The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities 
- The report reviews key players involved in the therapeutics development for Plague and enlists all their major and minor projects
- The report summarizes all the dormant and discontinued pipeline projects 
- A review of the Plague products under development by companies and universities/research institutes based on information derived from company and industry-specific sources
- Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- A detailed assessment of monotherapy and combination therapy pipeline projects
- Coverage of the Plague pipeline on the basis of target, MoA, route of administration and molecule type
- Latest news and deals relating related to pipeline products

Reasons to buy

- Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Develop strategic initiatives by understanding the focus areas of leading companies
- Identify and understand important and diverse types of therapeutics under development for Plague
- Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline
- Devise corrective measures for pipeline projects by understanding Plague pipeline depth and focus of Indication therapeutics
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
- Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline
Table of Contents
Table of Contents 2
List of Tables 5
List of Figures 5
Introduction 6
Global Markets Direct Report Coverage 6
Plague Overview 7
Therapeutics Development 8
Pipeline Products for Plague - Overview 8
Pipeline Products for Plague - Comparative Analysis 9
Plague - Therapeutics under Development by Companies 10
Plague - Therapeutics under Investigation by Universities/Institutes 11
Plague - Pipeline Products Glance 12
Clinical Stage Products 12
Early Stage Products 13
Unknown Stage Products 14
Plague - Products under Development by Companies 15
Plague - Products under Investigation by Universities/Institutes 16
Plague - Companies Involved in Therapeutics Development 17
Aradigm Corporation 17
Grifols, S.A. 18
iBio, Inc. 19
Mucosis B.V. 20
Syntiron LLC 21
Tetraphase Pharmaceuticals Inc. 22
Plague - Therapeutics Assessment 23
Assessment by Monotherapy Products 23
Assessment by Combination Products 24
Assessment by Target 25
Assessment by Mechanism of Action 27
Assessment by Route of Administration 29
Assessment by Molecule Type 31
Drug Profiles 33
anthrax + plague vaccine - Drug Profile 33
Product Description 33
Mechanism of Action 33
R&D Progress 33
ARD-3100 - Drug Profile 34
Product Description 34
Mechanism of Action 34
R&D Progress 34
ciprofloxacin hydrochloride - Drug Profile 36
Product Description 36
Mechanism of Action 36
R&D Progress 36
plague vaccine - Drug Profile 37
Product Description 37
Mechanism of Action 37
R&D Progress 37
plague vaccine - Drug Profile 38
Product Description 38
Mechanism of Action 38
R&D Progress 38
plague vaccine - Drug Profile 39
Product Description 39
Mechanism of Action 39
R&D Progress 39
plague vaccine - Drug Profile 41
Product Description 41
Mechanism of Action 41
R&D Progress 41
plague vaccine - Drug Profile 42
Product Description 42
Mechanism of Action 42
R&D Progress 42
plague vaccine - Drug Profile 43
Product Description 43
Mechanism of Action 43
R&D Progress 43
plague vaccine - Drug Profile 44
Product Description 44
Mechanism of Action 44
R&D Progress 44
plague vaccine - Drug Profile 45
Product Description 45
Mechanism of Action 45
R&D Progress 45
plague vaccine - Drug Profile 46
Product Description 46
Mechanism of Action 46
R&D Progress 46
pneumonic plaque vaccine - Drug Profile 47
Product Description 47
Mechanism of Action 47
R&D Progress 47
Small Molecules to Inhibit Yoph Protein Tyrosine Phosphatase for Plague - Drug Profile 48
Product Description 48
Mechanism of Action 48
R&D Progress 48
TP-271 - Drug Profile 49
Product Description 49
Mechanism of Action 49
R&D Progress 49
Yersinia pestis vaccine - Drug Profile 51
Product Description 51
Mechanism of Action 51
R&D Progress 51
Plague - Recent Pipeline Updates 52
Plague - Dormant Projects 55
Plague - Discontinued Products 56
Plague - Product Development Milestones 57
Featured News & Press Releases 57
Mar 30, 2015: iBio European Plague Vaccine Patent Emerges From Opposition Period 57
Nov 19, 2012: UK Scientists Report On Efficacy Of Aradigm's Lipoquin Against Pneumonic Plague 57
Jun 05, 2008: Computer Sciences Corporation's DynPort Vaccine Company To Continue Plague Vaccine Development 59
Nov 18, 2005: Computer Sciences Corporation's DynPort Vaccine Company Reaches Milestone In Plague Vaccine Clinical Trial 59
May 17, 2005: Wake Forest Scientists Find New Combination Vaccine Effective Against Plague 59
Jan 10, 2005: Computer Sciences Corporation's DynPort Vaccine Company Enters Clinical Trial For Plague Vaccine Candidate 60
Appendix 61
Methodology 61
Coverage 61
Secondary Research 61
Primary Research 61
Expert Panel Validation 61
Contact Us 61
Disclaimer 62

List of Tables
Number of Products under Development for Plague, H2 2015 8
Number of Products under Development for Plague - Comparative Analysis, H2 2015 9
Number of Products under Development by Companies, H2 2015 10
Number of Products under Investigation by Universities/Institutes, H2 2015 11
Comparative Analysis by Clinical Stage Development, H2 2015 12
Comparative Analysis by Early Stage Development, H2 2015 13
Comparative Analysis by Unknown Stage Development, H2 2015 14
Products under Development by Companies, H2 2015 15
Products under Investigation by Universities/Institutes, H2 2015 16
Plague - Pipeline by Aradigm Corporation, H2 2015 17
Plague - Pipeline by Grifols, S.A., H2 2015 18
Plague - Pipeline by iBio, Inc., H2 2015 19
Plague - Pipeline by Mucosis B.V., H2 2015 20
Plague - Pipeline by Syntiron LLC, H2 2015 21
Plague - Pipeline by Tetraphase Pharmaceuticals Inc., H2 2015 22
Assessment by Monotherapy Products, H2 2015 23
Assessment by Combination Products, H2 2015 24
Number of Products by Stage and Target, H2 2015 26
Number of Products by Stage and Mechanism of Action, H2 2015 28
Number of Products by Stage and Route of Administration, H2 2015 30
Number of Products by Stage and Molecule Type, H2 2015 32
Plague Therapeutics - Recent Pipeline Updates, H2 2015 52
Plague - Dormant Projects, H2 2015 55
Plague - Discontinued Products, H2 2015 56

List of Figures
Number of Products under Development for Plague, H2 2015 8
Number of Products under Development for Plague - Comparative Analysis, H2 2015 9
Number of Products under Development by Companies, H2 2015 10
Number of Products under Investigation by Universities/Institutes, H2 2015 11
Comparative Analysis by Clinical Stage Development, H2 2015 12
Comparative Analysis by Early Stage Products, H2 2015 13
Assessment by Monotherapy Products, H2 2015 23
Number of Products by Top 10 Targets, H2 2015 25
Number of Products by Stage and Top 10 Targets, H2 2015 25
Number of Products by Top 10 Mechanism of Actions, H2 2015 27
Number of Products by Stage and Top 10 Mechanism of Actions, H2 2015 27
Number of Products by Top 10 Routes of Administration, H2 2015 29
Number of Products by Stage and Top 10 Routes of Administration, H2 2015 29
Number of Products by Top 10 Molecule Types, H2 2015 31
Number of Products by Stage and Top 10 Molecule Types, H2 2015 31

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