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Regulus Therapeutics Inc. - Product Pipeline Review - 2015

Published: Aug-2015 | Format: PDF | Global Markets Direct | Number of pages: 40 | Code: MRS - 35153

Regulus Therapeutics Inc. - Product Pipeline Review - 2015

Summary

Global Markets Direct’s, ‘Regulus Therapeutics Inc. - Product Pipeline Review - 2015’, provides an overview of the Regulus Therapeutics Inc.’s pharmaceutical research and development focus.

This report provides comprehensive information on the current therapeutic developmental pipeline of Regulus Therapeutics Inc.’s, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. It also reviews latest updates, and featured news and press releases, along with special features on late-stage and discontinued projects.

Global Markets Direct’s report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Direct’s proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct’s team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease.

Scope

- The report provides brief overview of Regulus Therapeutics Inc. including business description, key information and facts, and its locations and subsidiaries
- The report reviews current pipeline of Regulus Therapeutics Inc.’s human therapeutic division and enlists all their major and minor projects
- The report features product description and descriptive mechanism of action for key pipeline products along with the product’s developmental history and major milestones 
- Special feature on out-licensed and partnered product portfolio
- The report summarizes all the dormant and discontinued pipeline projects
- Latest company statement 
- Latest news and deals relating to the Regulus Therapeutics Inc.’s pipeline products

Reasons to buy

- Evaluate Regulus Therapeutics Inc.’s strategic position with total access to detailed information on its product pipeline
- Assess the growth potential of Regulus Therapeutics Inc. in its therapy areas of focus
- Identify new drug targets and therapeutic classes in the Regulus Therapeutics Inc.’s R&D portfolio and develop key strategic initiatives to reinforce pipeline in those areas
- Exploit in-licensing opportunities by identifying windows of opportunity to fill portfolio gaps
- Develop strategic initiatives by understanding the focus areas of Regulus Therapeutics Inc. and exploit collaboration and partnership opportunities
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Plan mergers and acquisitions effectively by identifying the most promising pipeline of Regulus Therapeutics Inc.
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
- Explore the dormant and discontinued projects of Regulus Therapeutics Inc. and identify potential opportunities in those areas
- Avoid Intellectual Property Rights related issues
Table of Contents
Table of Contents 2
List of Tables 4
List of Figures 4
Regulus Therapeutics Inc. Snapshot 5
Regulus Therapeutics Inc. Overview 5
Key Information 5
Key Facts 5
Regulus Therapeutics Inc. - Research and Development Overview 6
Key Therapeutic Areas 6
Regulus Therapeutics Inc. - Pipeline Review 8
Pipeline Products by Stage of Development 8
Pipeline Products - Monotherapy 9
Regulus Therapeutics Inc. - Pipeline Products Glance 10
Regulus Therapeutics Inc. - Clinical Stage Pipeline Products 10
Phase II Products/Combination Treatment Modalities 10
Phase I Products/Combination Treatment Modalities 11
Regulus Therapeutics Inc. - Early Stage Pipeline Products 12
Preclinical Products/Combination Treatment Modalities 12
Discovery Products/Combination Treatment Modalities 13
Regulus Therapeutics Inc. - Drug Profiles 14
RG-101 14
Product Description 14
Mechanism of Action 14
R&D Progress 14
RG-012 17
Product Description 17
Mechanism of Action 17
R&D Progress 17
Antisense RNAi Oligonucleotide to Inhibit MicroRNA-10b for Metastatic Breast Cancer and Glioblastoma Multiforme 19
Product Description 19
Mechanism of Action 19
R&D Progress 19
Antisense RNAi Oligonucleotide to Inhibit MicroRNA-21 for Hepatocellular Carcinoma 21
Product Description 21
Mechanism of Action 21
R&D Progress 21
Antisense RNAi Oligonucleotide to Inhibit miR-221 and miR-222 for Hepatocellular Carcinoma 23
Product Description 23
Mechanism of Action 23
R&D Progress 23
Antisense RNAi Oligonucleotides for Oncology and Orphan Diseases 25
Product Description 25
Mechanism of Action 25
R&D Progress 25
RG-125 26
Product Description 26
Mechanism of Action 26
R&D Progress 26
Antisense RNAi Oligonucleotide to Inhibit MicroRNA for Metabolic Disease 27
Product Description 27
Mechanism of Action 27
R&D Progress 27
Regulus Therapeutics Inc. - Pipeline Analysis 28
Regulus Therapeutics Inc. - Pipeline Products by Target 28
Regulus Therapeutics Inc. - Pipeline Products by Route of Administration 29
Regulus Therapeutics Inc. - Pipeline Products by Molecule Type 30
Regulus Therapeutics Inc. - Pipeline Products by Mechanism of Action 31
Regulus Therapeutics Inc. - Recent Pipeline Updates 32
Regulus Therapeutics Inc. - Dormant Projects 36
Regulus Therapeutics Inc. - Discontinued Pipeline Products 37
Discontinued Pipeline Product Profiles 37
Antisense RNAi Oligonucleotide to Inhibit MicroRNA-19 for Cancer 37
Regulus Therapeutics Inc. - Locations And Subsidiaries 38
Head Office 38
Appendix 39
Methodology 39
Coverage 39
Secondary Research 39
Primary Research 39
Expert Panel Validation 39
Contact Us 39
Disclaimer 40

List of Tables
Regulus Therapeutics Inc., Key Information 5
Regulus Therapeutics Inc., Key Facts 5
Regulus Therapeutics Inc. - Pipeline by Indication, 2015 7
Regulus Therapeutics Inc. - Pipeline by Stage of Development, 2015 8
Regulus Therapeutics Inc. - Monotherapy Products in Pipeline, 2015 9
Regulus Therapeutics Inc. - Phase II, 2015 10
Regulus Therapeutics Inc. - Phase I, 2015 11
Regulus Therapeutics Inc. - Preclinical, 2015 12
Regulus Therapeutics Inc. - Discovery, 2015 13
Regulus Therapeutics Inc. - Pipeline by Target, 2015 28
Regulus Therapeutics Inc. - Pipeline by Route of Administration, 2015 29
Regulus Therapeutics Inc. - Pipeline by Molecule Type, 2015 30
Regulus Therapeutics Inc. - Pipeline Products by Mechanism of Action, 2015 31
Regulus Therapeutics Inc. - Recent Pipeline Updates, 2015 32
Regulus Therapeutics Inc. - Dormant Developmental Projects,2015 36
Regulus Therapeutics Inc. - Discontinued Pipeline Products, 2015 37

List of Figures
Regulus Therapeutics Inc. - Pipeline by Top 10 Indication, 2015 7
Regulus Therapeutics Inc. - Pipeline by Stage of Development, 2015 8
Regulus Therapeutics Inc. - Monotherapy Products in Pipeline, 2015 9
Regulus Therapeutics Inc. - Pipeline by Top 10 Target, 2015 28
Regulus Therapeutics Inc. - Pipeline by Top 10 Route of Administration, 2015 29
Regulus Therapeutics Inc. - Pipeline by Top 10 Molecule Type, 2015 30
Regulus Therapeutics Inc. - Pipeline Products by Top 10 Mechanism of Action, 2015 31

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