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Restless Legs Syndrome - Pipeline Review, H1 2015

Published: Jan-2015 | Format: PDF | Global Markets Direct | Number of pages: 47 | Code: MRS - 18147


Global Markets Directs, Restless Legs Syndrome Pipeline Review, H1 2015, provides an overview of the Restless Legs Syndromes therapeutic pipeline.

This report provides comprehensive information on the therapeutic development for Restless Legs Syndrome, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases. It also reviews key players involved in the therapeutic development for Restless Legs Syndrome and special features on late-stage and discontinued projects.

Global Markets Directs report features investigational drugs from across globe covering over 20 therapy areas and nearly 3,000 indications. The report is built using data and information sourced from Global Markets Directs proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Directs team. Drug profiles/records featured in the report undergoes periodic updation following a stringent set of processes that ensures that all the profiles are updated with the latest set of information. Additionally, processes including live news & deals tracking, browser based alert-box and clinical trials registries tracking ensure that the most recent developments are captured on a real time basis.

The report enhances decision making capabilities and help to create effective counter strategies to gain competitive advantage. It strengthens R&D pipelines by identifying new targets and MOAs to produce first-in-class and best-in-class products.

Scope

The report provides a snapshot of the global therapeutic landscape of Restless Legs Syndrome
The report reviews key pipeline products under drug profile section which includes, product description, MoA and R&D brief, licensing and collaboration details & other developmental activities
The report reviews key players involved in the therapeutics development for Restless Legs Syndrome and enlists all their major and minor projects
The report summarizes all the dormant and discontinued pipeline projects 
A review of the Restless Legs Syndrome products under development by companies and universities/research institutes based on information derived from company and industry-specific sources
Pipeline products coverage based on various stages of development ranging from pre-registration till discovery and undisclosed stages
A detailed assessment of monotherapy and combination therapy pipeline projects
Coverage of the Restless Legs Syndrome pipeline on the basis of target, MoA, route of administration and molecule type
Latest news and deals relating related to pipeline products

Reasons to buy

Provides strategically significant competitor information, analysis, and insights to formulate effective R&D development strategies
Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
Develop strategic initiatives by understanding the focus areas of leading companies
Identify and understand important and diverse types of therapeutics under development for Restless Legs Syndrome
Plan mergers and acquisitions effectively by identifying key players of the most promising pipeline
Devise corrective measures for pipeline projects by understanding Restless Legs Syndrome pipeline depth and focus of Indication therapeutics
Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline

Table Of Content

Table of Contents 2
List of Tables 4
List of Figures 4

Introduction 5
Global Markets Direct Report Coverage 5
Restless Legs Syndrome Overview 6
Therapeutics Development 7
Pipeline Products for Restless Legs Syndrome - Overview 7
Pipeline Products for Restless Legs Syndrome - Comparative Analysis 8
Restless Legs Syndrome - Therapeutics under Development by Companies 9
Restless Legs Syndrome - Pipeline Products Glance 10
Late Stage Products 10
Clinical Stage Products 11
Early Stage Products 12
Restless Legs Syndrome - Products under Development by Companies 13
Restless Legs Syndrome - Companies Involved in Therapeutics Development 14
Alexza Pharmaceuticals, Inc. 14
Ascendis Pharma A/S 15
Hisamitsu Pharmaceutical Co., Inc. 16
Ligand Pharmaceuticals, Inc. 17
Omeros Corporation 18
Purdue Pharma L.P. 19
Serina Therapeutics, Inc. 20
Restless Legs Syndrome - Therapeutics Assessment 21
Assessment by Monotherapy Products 21
Assessment by Combination Products 22
Assessment by Target 23
Assessment by Mechanism of Action 25
Assessment by Route of Administration 27
Assessment by Molecule Type 29
Drug Profiles 30
(naloxone hydrochloride + oxycodone hydrochloride) ER - Drug Profile 30
Product Description 30
Mechanism of Action 30
R&D Progress 30
ACP-006 - Drug Profile 32
Product Description 32
Mechanism of Action 32
R&D Progress 32
aplindore fumarate - Drug Profile 33
Product Description 33
Mechanism of Action 33
R&D Progress 33
AZ-008 - Drug Profile 34
Product Description 34
Mechanism of Action 34
R&D Progress 34
OMS-527 - Drug Profile 35
Product Description 35
Mechanism of Action 35
R&D Progress 35
ropinirole hydrochloride - Drug Profile 37
Product Description 37
Mechanism of Action 37
R&D Progress 37
SER-214 - Drug Profile 38
Product Description 38
Mechanism of Action 38
R&D Progress 38
Restless Legs Syndrome - Recent Pipeline Updates 39
Restless Legs Syndrome - Dormant Projects 41
Restless Legs Syndrome - Discontinued Products 42
Restless Legs Syndrome - Product Development Milestones 43
Featured News & Press Releases 43
Oct 24, 2014: Mundipharma receives Positive CHMP Opinion for Targin (oxycodone / naloxone) for the treatment of Restless Legs Syndrome 43
Jan 07, 2014: Mundipharma receives positive European Commission decision on Targin (oxycodone/naloxone) for the treatment of Restless Legs Syndrome 43
Nov 19, 2013: New data show efficacy of prolonged release TARGIN (oxycodone / naloxone) in the treatment of severe restless legs syndrome 44
Oct 16, 2008: Neurogen Announces Positive Top-Line Results From Two Phase II Trials For Aplindore In Restless Legs Syndrome And Parkinson's Disease 45

Appendix 46
Methodology 46
Coverage 46
Secondary Research 46
Primary Research 46
Expert Panel Validation 46
Contact Us 46
Disclaimer 47

List of Tables

Number of Products under Development for Restless Legs Syndrome, H1 2015 7
Number of Products under Development for Restless Legs Syndrome - Comparative Analysis, H1 2015 8
Number of Products under Development by Companies, H1 2015 9
Comparative Analysis by Late Stage Development, H1 2015 10
Comparative Analysis by Clinical Stage Development, H1 2015 11
Comparative Analysis by Early Stage Development, H1 2015 12
Products under Development by Companies, H1 2015 13
Restless Legs Syndrome - Pipeline by Alexza Pharmaceuticals, Inc., H1 2015 14
Restless Legs Syndrome - Pipeline by Ascendis Pharma A/S, H1 2015 15
Restless Legs Syndrome - Pipeline by Hisamitsu Pharmaceutical Co., Inc., H1 2015 16
Restless Legs Syndrome - Pipeline by Ligand Pharmaceuticals, Inc., H1 2015 17
Restless Legs Syndrome - Pipeline by Omeros Corporation, H1 2015 18
Restless Legs Syndrome - Pipeline by Purdue Pharma L.P., H1 2015 19
Restless Legs Syndrome - Pipeline by Serina Therapeutics, Inc., H1 2015 20
Assessment by Monotherapy Products, H1 2015 21
Assessment by Combination Products, H1 2015 22
Number of Products by Stage and Target, H1 2015 24
Number of Products by Stage and Mechanism of Action, H1 2015 26
Number of Products by Stage and Route of Administration, H1 2015 28
Number of Products by Stage and Molecule Type, H1 2015 29
Restless Legs Syndrome Therapeutics - Recent Pipeline Updates, H1 2015 39
Restless Legs Syndrome - Dormant Projects, H1 2015 41
Restless Legs Syndrome - Discontinued Products, H1 2015 42

List of Figures

Number of Products under Development for Restless Legs Syndrome, H1 2015 7
Number of Products under Development for Restless Legs Syndrome - Comparative Analysis, H1 2015 8
Number of Products under Development by Companies, H1 2015 9
Comparative Analysis by Early Stage Products, H1 2015 12
Assessment by Monotherapy Products, H1 2015 21
Number of Products by Top 10 Targets, H1 2015 23
Number of Products by Stage and Top 10 Targets, H1 2015 24
Number of Products by Top 10 Mechanism of Actions, H1 2015 25
Number of Products by Stage and Top 10 Mechanism of Actions, H1 2015 26
Number of Products by Top 10 Routes of Administration, H1 2015 27
Number of Products by Stage and Top 10 Routes of Administration, H1 2015 28
Number of Products by Stage and Top 10 Molecule Types, H1 2015 29

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