Development of heart in vitro is usually difficult thus mimicking its growth is something the researchers are now working on. According to Tokyo Medical and Dental University (TMDU), they have created a 3D functional heart organoids using mouse embryonic stem cells as those cells have a close resemblance to the development of human heart. The heart comprises of many layers of tissues that include various cell types such as connective tissue cells, working heart muscle, and cells forming blood
The glial cells and neurons are the ones that make up the nervous system. And in the glial cells, the astrocytes are found to be present in abundance. One of the important functions of the astrocytes is to capture glucose from the blood stream to generate energy and carry out essential neuronal activity. All these activities ensure the cognitive functions are performed perfectly. The molecules, including type 1 (CB1), present in the astrocytes help the neurons control astrocyte activity. The a
Right now, the frontline healthcare workers are forced to wear personal protective equipment (PPE) which comprises of goggles, face visors, and respiratory protective equipment to avoid contracting COVID-19 while at work. These essentials have become an essential part of their working life. Currently, all the medical staffs are wearing facial PPE that too for an extended period of time to avoid the entry of the SARS-CoV-2 virus into their body. But, the use of PPE for hours together is known t
A team from So Paulo State University has found the exercise hormone named irisin to have the ability to fight COVID-19. The therapeutic effect of irisin is currently being explored to help save more lives. On studying adipose cell gene regulation, the researchers found a connection between irisin modulated genes and the replication of the coronavirus SARS-CoV-2 in human cells. The transcriptome was used to study the non-infected adipose cells. The new findings published in Molecular and Cellu
Amid the COVID-19 pandemic, the shortage in the supply of personal protective equipment is only sky rocketing and thereby increasing the risks. Thus, the researchers from the University of Cincinnati have recently developed a face covering using the common household fabrics itself. The new development will prove as beneficial as a single-use N95 respirator or surgical mask. This new suitable and highly protective alternative could be made using a hungry little caterpillar. The caterpillar made
Researchers from Cologne and Helsinki have recently developed a novel method to prevent hair loss, which basically occurs when hair follicle stem cells that are needed for hair growth switch their metabolic state in presence of low concentration of oxygen in order to prolong their life. The skin and hair follicles are the tissues that are majorly exposed to environmental damage like ultraviolet (UV) light. Generally, the damaged tissues are constantly renewed and removed. The researchers are w
In the medical field, the researchers are always carrying out promising breakthroughs inside the laboratory. The in-vitro culture study is not only cost-effective but also easy to perform such that better insight of the interaction between particular chemical compounds, including toxins, nutrients, drugs, and microorganisms or cells. Moreover, to understand the toxicity of a compound this is an efficient and precise way to differentiate the toxicity killed and viable cells. There are many exi
A team has developed human retinas in the lab with the purpose of using it to replace specific types of cells that are affected by the genetic eye diseases. This new finding is expected to speed up the development of latest therapies. The Institute for Molecular and Clinical Ophthalmology Basel (IOB) researchers along with their colleagues from the Novartis Institutes for BioMedical Research developed retina that is important for capturing and managing the visual information. In the human body
The University of Leeds researchers have recently created a new and rapid method for diagnosing diseases in patients. The researchers developed a system that keenly monitors every molecule in an individual to identify the presence of any kind of abnormality or disease in blood. By molecules, the researcher mean biomarkers, which are present in billions in the blood and specific diseases are found to have particular biomarkers spiked up. The new system has already proved positive in detecting a
A team from the University of Valencia (UV) has developed a new system using colorimetric sensors to predict the presence of -hydroxybutyric acid (GHB) in a beverage through any change in color. GHB is little salty, odorless, and colorless compound that is known to override the will of a person when consumed. The team has already patented their new finding as it is a new and safe method in detecting the substance in any soft drink and alcoholic beverage. As GHB is an easily available molecule,